The concept of the show revolves around roommates Bugs and Daffy living in a suburb of Los Angeleswith "colorful neighbors" and other characters including Lola Bunny, Tina Russo, Porky Pig, Foghorn Leghorn, Elmer Fudd, Sylvester, Tweety, Granny, Gossamer, Yosemite Sam, Speedy Gonzales, Marvin the Martian, Pete Puma, and more. The show's plots contain fewer visual gags and are more adult-oriented and dialogue-driven than has been seen in past Looney Tunes shows such as love triangles, employment, and rooming.
- Jeff Bergman as Bugs Bunny / Daffy Duck
- Bob Bergen as Porky Pig
- Maurice McMarche as Yosemite Sam’
- Kristen Wiig as Lola Bunny
- Jim Cummings as Tasmanian Devil
- June Foray as Granny